Alzheimer’s & Dementia from Fluoridation Record

 The Fluoridation RecordJan. 3, 2022
A newsletter of East Coast Science News, Belchertown, Massachusetts, USA
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Alzheimer’s & Dementia report found drugs that reduce fluoride’s harm in rats
Alzheimer’s & Dementia, the journal of the Alzheimer Association, has published a new
study from the Manipal College of Pharmaceutical Sciences in India that reports that prenatal
and continuing treatment with metformin and dehydrozingerone (DHZ) have “neuroprotective
ability” in Wistar rats exposed prenatally to high concentrations of fluoride in drinking water.
The report includes an unusually blunt assessment of fluoride’s neurotoxic effects, with
the authors stating, “It has been reported that exposure to excess amounts of fluoride either
through drinking water or other sources impairs vital functions of the body and can prove to be
toxic especially for the central nervous system. Many studies have shown that sodium fluoride
(NaF) crosses the blood brain barrier in early developmental stages and causes impairments
related to learning and memory, anxiety, decreased locomotor ability and in some cases,
depression-like behaviour especially in children.”
The authors report that behavioral adverse effects, and physiological and cellular effects

of the fluoride on the hippocampus were lessened by the drug treatment.
“It was also observed that treatment with metformin & DHZ was able to ameliorate the
cognitive impairment, improve condition of oxidative stress & decrease neuronal degeneration
in rat pups,” they concluded.
https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.058668
More than a quarter of China faces high risk of fluoride exposure
A new model of groundwater fluoride contamination in China has found that over 27
percent of the land mass contains areas of high risk fluoride exposure.
The authors estimate that 89 million rural people in China face a health risk due to high
exposure to fluoride.
The report contains a map showing the areas of endemic fluorosis in China. These are
found particularly in the western half of the country where much of the water exceeds 1.5
milligrams per liter fluoride.
The authors conclude, “The high risk areas are mainly located in western provinces of
Xinjiang, Tibet, Qinghai, and Sichuan, and the northern provinces of Inner Mongolia, Hebei and
Shandong. The total number of people estimated to be potentially at risk of fluorosis due to the
use of untreated high fluoride groundwater as drinking water is about 89 million, or 6% of the
population.”
https://www.sciencedirect.com/science/article/abs/pii/S1001074221002710?via%3Dihub
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The Fluoridation Record is published weekly at Belchertown, Massachusetts by East Coast
Science News, P.O. Box 797, Belchertown, MA 01007 USA. Copyright 2022. All rights reserved.
Michael F. Dolan, editor. January 3, 2022, Vol. 6 No. 110. The newsletter is distributed by email
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