Red Light ‘Triples Testicle Function’ Studies Show
30
Oct
Oct
Most organs and glands of the body are covered by several inches of
either bone, muscle, fat, skin or other tissues, making direct light
exposure impractical, if not impossible. However, one of the notable
exceptions is the male testes.
Is it advisable to shine red light directly on one’s testicles?
Research is highlighting several interesting benefits to testicular red light exposure:
Healthy spermatogenesis, or the creation of sperm cells, happens in the testicles, not so far from the production of androgens in the Leydig cells. The two are highly correlated in fact – meaning that high testosterone levels = high sperm quality and vice versa. It’s rare to find a low testosterone man with great sperm quality.
Sperm are produced in the seminiferous tubules of the testes, in a multi-step process involving several cell divisions and maturation of these cells. Various studies have established a very linear relationship between ATP/energy production and spermatogenesis:
This applies not only to the sperm production in the testicles, but also directly to the health of free sperm cells post-ejaculation. For example studies have been done on in vitro fertilization (IVF), showing superior outcomes under red light in both mammals and fish sperm. The effect is especially profound when it comes to sperm motility, or ability to ‘swim’, as the tail of sperm cells are powered by a row of red light sensitive mitochondria.
Some light, it seems, is good for our hormones. Conversion of skin cholesterol into vitamin D3 sulfate is a direct link. Though perhaps more importantly, the improvement in oxidative metabolism and ATP production from red/infrared wavelengths has broad reaching, and often underestimated, effects on the body. After all, cellular energy production is the basis of all functions of life.
More recently, studies have been done on direct sunlight exposure, firstly to the torso, which reliably increases male’s testosterone levels by anywhere from 25% to 160% depending on the person. Sunlight exposure directly to the testes though has an even more profound effect, boosting testosterone production in Leydig cells by an average of 200% – a large increase over baseline levels.
Studies linking light, particularly red light, to the testicular function of animals have been performed for almost 100 years now. Initial experiments focused on male birds and small mammals such as mice, showing effects such as sexual activation and recrudescence. Testicular stimulation by red light has been researched for almost a century, with studies linking it to healthy testicular growth and superior reproductive outcomes in almost all cases. More recent human studies support the same theory, showing potentially even more positive results compared to birds/mice, with preliminary results showing a steady, dose-dependent jump in testosterone levels.
Testicular function, as mentioned above, is dependent on energy production. While this can be said about practically any tissue in the body, there is evidence that it is especially true for the testes.
Explained in greater detail on our red light therapy page, the mechanism that red wavelengths work is to stimulate ATP production (which can be thought of as cellular energy currency) in our mitochondria’s respiratory chain (look into cytochrome oxidase – a photoreceptive enzyme – for more info), increasing the energy available to the cell – this applies to Leydig cells (testosterone producing cells) just as much. Energy production and cellular function are commensurate, meaning more energy = more testosterone production.
More so than that, whole body energy production, as correlated with / measured by active thyroid hormone levels, is known to stimulate steroidogenesis (or testosterone production) directly in the Leydig cells.
Another potential mechanism involves a seperate class of photoreceptive proteins, known as ‘opsin proteins’. The human testes are especially abundant with various of these highly specific photoreceptors including OPN3, which are ‘activated’, much like cytochrome, specifically by wavelengths of light. Stimulation of these testicular proteins by red light induces cellular responses that may ultimately lead to increased testosterone production, amongst other things, although research is still in the preliminary stages regarding these proteins and metabolic pathways. These type of photoreceptive proteins are also found in the eyes and also, interestingly, the brain.
Is it advisable to shine red light directly on one’s testicles?
Research is highlighting several interesting benefits to testicular red light exposure:
Fertility Boosted
Sperm quality is the primary measure of fertility in men, as the viability of spermatozoa is generally the limiting factor to successful reproduction (from the male’s side).Healthy spermatogenesis, or the creation of sperm cells, happens in the testicles, not so far from the production of androgens in the Leydig cells. The two are highly correlated in fact – meaning that high testosterone levels = high sperm quality and vice versa. It’s rare to find a low testosterone man with great sperm quality.
Sperm are produced in the seminiferous tubules of the testes, in a multi-step process involving several cell divisions and maturation of these cells. Various studies have established a very linear relationship between ATP/energy production and spermatogenesis:
- Drugs and compounds which interfere with mitochondrial energy metabolism in general (i.e. Viagra, ssris, statins, alcohol, etc.) have an extremely negative effect on sperm production.
- Drugs/compounds which support ATP production in mitochondria (thyroid hormones, caffeine, magnesium, etc.) boost sperm counts and general fertility.
This applies not only to the sperm production in the testicles, but also directly to the health of free sperm cells post-ejaculation. For example studies have been done on in vitro fertilization (IVF), showing superior outcomes under red light in both mammals and fish sperm. The effect is especially profound when it comes to sperm motility, or ability to ‘swim’, as the tail of sperm cells are powered by a row of red light sensitive mitochondria.
Summary
- In most cases, red light therapy on the testicle area shortly before sexual intercourse would produce a greater chance of successful fertilization.
- Furthermore, consistent red light therapy over the days prior to sexual intercourse would even further increase chances, not to mention reduce chances of abnormal sperm production.
Testosterone Levels Potentially Tripled
It has been known scientifically since the 1930s that light in general can help males to produce more of the androgen testosterone. Initial studies back then examined how isolated light sources on the skin and body affect hormone levels, showing a significant improvement by using incandescent bulbs and artificial sunlight.Some light, it seems, is good for our hormones. Conversion of skin cholesterol into vitamin D3 sulfate is a direct link. Though perhaps more importantly, the improvement in oxidative metabolism and ATP production from red/infrared wavelengths has broad reaching, and often underestimated, effects on the body. After all, cellular energy production is the basis of all functions of life.
More recently, studies have been done on direct sunlight exposure, firstly to the torso, which reliably increases male’s testosterone levels by anywhere from 25% to 160% depending on the person. Sunlight exposure directly to the testes though has an even more profound effect, boosting testosterone production in Leydig cells by an average of 200% – a large increase over baseline levels.
Studies linking light, particularly red light, to the testicular function of animals have been performed for almost 100 years now. Initial experiments focused on male birds and small mammals such as mice, showing effects such as sexual activation and recrudescence. Testicular stimulation by red light has been researched for almost a century, with studies linking it to healthy testicular growth and superior reproductive outcomes in almost all cases. More recent human studies support the same theory, showing potentially even more positive results compared to birds/mice, with preliminary results showing a steady, dose-dependent jump in testosterone levels.
Why exactly does red light on testes have dramatic effects on testosterone?
Testicular function, as mentioned above, is dependent on energy production. While this can be said about practically any tissue in the body, there is evidence that it is especially true for the testes.
Explained in greater detail on our red light therapy page, the mechanism that red wavelengths work is to stimulate ATP production (which can be thought of as cellular energy currency) in our mitochondria’s respiratory chain (look into cytochrome oxidase – a photoreceptive enzyme – for more info), increasing the energy available to the cell – this applies to Leydig cells (testosterone producing cells) just as much. Energy production and cellular function are commensurate, meaning more energy = more testosterone production.
More so than that, whole body energy production, as correlated with / measured by active thyroid hormone levels, is known to stimulate steroidogenesis (or testosterone production) directly in the Leydig cells.
Another potential mechanism involves a seperate class of photoreceptive proteins, known as ‘opsin proteins’. The human testes are especially abundant with various of these highly specific photoreceptors including OPN3, which are ‘activated’, much like cytochrome, specifically by wavelengths of light. Stimulation of these testicular proteins by red light induces cellular responses that may ultimately lead to increased testosterone production, amongst other things, although research is still in the preliminary stages regarding these proteins and metabolic pathways. These type of photoreceptive proteins are also found in the eyes and also, interestingly, the brain.
Summary
- In most cases, red light therapy directly on the testicles for short, regular periods would raise testosterone levels over time.
- Downstream this would lead to a holistic effect on the body, raising focus, improving mood, increasing muscle mass, bone strength and lowering excess body fat.
Type of light exposure is crucial
Red light can come from a variety of sources; it is contained in the wider spectra of sunlight, most home/work lights, street lights and so on. The problem with these light sources is that they also contain contradictory wavelengths such as UV (in the case of sunlight) and blue (in the case of most home/street lights). Additionally, the testicles are especially sensitive to heat, more so than other parts of the body. There’s no point applying beneficial light if you are simultaneously cancelling the effects with harmful light or excess heat.Blue & UV light’s effects
Metabolically, blue light can be thought of as the opposite of red light. While red light improves cellular energy production, blue light worsens it. Blue light specifically damages the cytochrome enzyme in mitochondria, preventing ATP and carbon dioxide production. This can be positive in certain situations such as acne (where the problematic bacteria are killed), but over time in humans this leads to an inefficient metabolic state similar to diabetes. UV or ultraviolet light is even worse, having all of the negative aspects of blue light magnified, and able to penetrate the skin deeper – exerting damage on a more profound level.Red Light vs. Sunlight on testicles
Sunlight has definite beneficial effects – vitamin D production, improved mood, increased energy metabolism (in small doses) and so on, but it is not without its downsides. Too much exposure and you not only lose all benefits, but create inflammation and damage in the form of sunburn, eventually contributing the skin cancer. Sensitive areas of the body with thin skin are especially prone to this damage and inflammation from sunlight – no area of the body more so than the testes. Isolated sources of red light such as LEDs are better, with none of the harmful blue & UV wavelengths and so no risk of sunburn, cancer or testicular inflammation.Don’t heat the testicles
Male testicles hang outside of the torso for a specific reason – they operate most efficiently at 35°C (95°F), which is a full two degrees below normal body temperature of 37°C (98.6°F). Many types of lamps and bulbs used by some for light therapy (such as incandescents, heat lamps, infrared lamps at 1000nm+) give off a significant amount of heat and therefore are NOT suitable for use on the testicles. Heating the testicles while attempting to apply light would give negative results. The only ‘cold’/efficient sources of red light are LEDs.Bottom Line
- Red or infrared light from an LED source (600-950nm) can be safely applied to the testes without risk of side effects or damage
- while delivering all of the benefits as detailed above (improved fertility, improved testosterone production, etc.).
- Sunlight can also be used on the testes but only for short periods and it is not without risks.
- Avoid exposure to blue/UV.
- Avoid any sort of heat lamp/incandescent bulb.
Recommended Light Devices
References
Iurshin VV, Sergienko NF, Illarionov VE. Etiopathogenetic basis for using magnetolaser therapy in the complex treatment of male infertility. Urologiia. 2003 Mar-Apr;(2):23-5.
Reza Salman Yazdi, Simin Bakhshi, Firooz Jannat Alipoor, Mohammad Reza Akhoond. Effect of 830-nm diode laser irradiation on human sperm motility. Lasers Med Sci (2014) 29:97–104
Ross S. Firestone, Navid Esfandiari, Sergey I. Moskovtsev et al. The Effects of Low-Level Laser Light Exposure on Sperm Motion Characteristics and DNA Damage. Journal of Andrology, Vol. 33, No. 3, May/June 2012
Taha MF, Valojerdi MR. Quantitative and qualitative changes of the seminiferous epithelium induced by Ga. Al. As. (830 nm) laser irradiation. Lasers in surgery and medicine 2004; 34: 352-359.
Jin-Chul Ahn, Young-Hoon Kim, Chung-Ku Rhee. The effects of low level laser therapy (LLLT) on the testis in elevating serum testosterone levels in rats. Biomedical Research 2013; 24 (1): 28-32
NM Biswas, R Biswas, NM Biswas and Late H Mandal. Effect of continuous light on spermatogenesis and testicular steroidogenesis in rats. Nepal Med Coll J 2013; 15(1): 62-64
Z. Abdel-Salam, M.A. Harith. Laser researches on livestock semen and oocytes: A brief review. Journal of Advanced Research. Volume 6, Issue 3, May 2015, Pages 311–317
Peterson, R, N., and Freund, M. (1970). ATP synthesis and oxidative metabolism in human spermatozoa. Biol. Reprod. 3, 47–54.
Irani S, Monfared SSMS, Akbari-Kamrani M, Abdol-lahi M, Larijani B. Effect of low-level laser irradiation on in vitro function of pancreatic islets. Transplantation Proceedings 2009; 41: 4313-4315.
Rajender S, Monica MG, Walter L, Agarwal A. Thyroid, spermatogenesis, and male infertility. Front Biosci (Elite Ed). 2011 Jun 1;3:843-55.
Mendis-Handagama SM1, Siril Ariyaratne HB. Leydig cells, thyroid hormones and steroidogenesis. Indian J Exp Biol. 2005 Nov;43(11):939-62.
Kolarova H, Ditrichova D, Waqner J. Penetration for the laser light into the skin in vitro. Lasers in surg Med 1999; 24: 231.
Gildersleeve RP, Johnson WA. Effects of low intensity red light on testicular recrudescence in Japanese quail. Poult Sci. 1981 Feb;60(2):453-61.
Hance MW, Mason JI, Mendis-Handagama SM. Effect of photostimulation and non-stimulation of golden hamster from birth to early puberty on testis structure and function. Histol Histopathol 2009; 24: 1417-24.
Thomas Hume Bissonnette. Inhibition of the stimulating effect of red light on testis in sturnus vulgaris by a restricted diet. Inst of animal nutrition, Cambridge.
Biswas R, Sarkar M, Biswas NM. Protection of testicular activity by continuous light in rats treated with lithium. Med Sci Res 1994; 24: 297-8.
Harrison PC, Latshaw JD, Casey JM, McGinnis J. Influence of decreased length of different spectral photoperiods on testis development of domestic fowl. J Reprod Fertil. 1970 Jul;22(2):269-75.
Graefes Arch Clin Exp Ophthalmol 1993 Jul;231(7):416-23. Inhibition of cytochrome oxidase and blue-light damage in rat retina. Chen E. St. Erik’s Eye Hospital, Karolinska Institute, Stockholm, Sweden.
Sandro La Vignera, Rosita A Condorelli. Does alcohol have any effect on male reproductive function? A review of literature. Asian J Androl. 2013 Mar; 15(2): 221–225.
Huang YY, Chen ACH, Carroll JD, Hamblin MR. Bi-phasic dose response in low level light therapy. Dose-Response 2009; 7: 358-383.
Rana Begum, Michael B. Powner, Natalie Hudson, et al. Treatment with 670 nm Light Up Regulates Cytochrome C Oxidase Expression and Reduces Inflammation in an Age-Related Macular Degeneration Model. February 28, 2013. DOI: 10.1371/journal.pone.0057828
Azevedo LH, Aranha AC, Stolf SF, Eduardo CD, Vieira MM. Evaluation of low intensity laser effects on the thyroid gland of male mice. Photomedicine and laser surgery 2005; 23: 567-570.
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