Scientists Receive Green Light To “Resurrect The Dead” Using Stem Cells from Collective Evolution
In Brief
- The Facts:biotech
company Bioquark has been given the green light to 'resurrect' the
clinically dead using stem cells. They are attempting 'the reversal of
death.'
- Reflect On:How do you feel about this? Should we be trying to stay alive forever, in a sense? Do we, as a society, view death in a healthy manner? Should we know what happens at death? What are the implications of 'living forever?'
Death
is a controversial subject in the medical field for many reasons.
People rely on doctors to save them and their loved ones, but when fate
has its way, the whole world can feel out of order. And while the death
of a loved one may not feel final at first, we soon come to realize
that, at least for the living who remain, it does mark an end.
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That’s why it seems like a controversial
yet incredible move for a US biotechnology company called Bioquark to
have been given permission to recruit 20 clinically dead patients and
attempt to bring their central nervous systems back to life. They hope
to eliminate patients’ need to rely on machines by reanimating parts of
the upper spinal cord, where the lower brain stem is located, to
potentially energize vital body functions like breathing and heartbeats.
Trial participants will have been
declared certified dead and kept alive solely through life support
machines. “This represents the first trial of its kind and another step
towards the eventual reversal of death in our lifetime,” said CEO of Bioquark Inc., Ira Pastor.
The team, who was granted ethical permission from an Institutional
Review Board at the National Institutes of Health in the US and India to
begin trials on 20 subjects, is looking to recruit patients for its ReAnima Project as soon as possible.
The team will first complete a phase 1 trial, referred
to as a non-randomized, proof-of-concept study. This will determine
whether or not they are capable of reversing clinical brain
death through drug administration, nerve stimulation, and laser therapy.
They’ll also be looking at whether or not they can affect any changes
in the meninges of the brain, layers of tissue located between the skull
and the surface of the brain. Specifically, the team will be
investigating improvements in the patients’ pulse, blood oxygen
saturation, blood pressure, and respiration.
The team will first seek permission from
the families of the clinically dead, and then will proceed to treat the
20 chosen individuals over a six-week period in Anupam Hospital in
Rudrapur, India. These will then be monitored for several months, where
the researchers will determine if any changes have been made. “We hope
to see results within the first two to three months,” Pastor said.
To attempt to bring the patients back from the dead, Bioquark has administered four different types of treatments, which include:
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- Injecting simple protein chains called peptides into the patients’ spinal cord on a daily basis.
- Injecting stem cells into their brains twice weekly.
- Using the non-invasive treatment called transcranial laser therapy to activate the body’s natural recovery processes.
- Using another non-invasive technique called nerve stimulation, which involves delivering electrical impulses to the median nerve of the upper limb.
“To undertake such a complex initiative,
we are combining biologic regenerative medicine tools with other
existing medical devices typically used for stimulation of the central
nervous system, in patients with other severe disorders of
consciousness,” Pastor noted.
The researchers are hoping that, if they
can get patients’ brains to work again, and since many clinically dead
can retain certain functions, like processing waste, digesting
nutrients, healing wounds, and growing and maturing, people will have
the chance to regain some semblance of life. But for now, the team is
just trying to take it one step at a time.
“It is a long-term vision of ours that a
full recovery in such patients is a possibility, although that is not
the focus of this first study – but it is a bridge to that eventuality,”
Pastor said.
And Sergei Pavlian, founder and president of Bioquark Inc., added:
Through our study, we will gain unique insights into the state of human brain death, which will have important connections to future therapeutic development for other severe disorders of consciousness, such as coma, and the vegetative and minimally conscious states, as well as a range of degenerative CNS conditions, including Alzheimer’s and Parkinson’s disease,” said Sergei Paylian, the founder and chief science officer of Bioquark.
Check out the trial outline here.
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