COVID Vaccination May Impair Innate Immune Function
Epidemiologist and researcher, Paul Alexander, PhD warns that COVID-19 vaccination could permanently damage the innate immune system in children and prevent it from functioning and developing normally.1
The innate (cellular) immune system acts as the first line of defense against the challenge of pathogens causing infectious disease. When the innate immune system identifies pathogenic viruses, bacteria, parasites or toxins, it activates cells to attack and resist or repair damage.2 Exposure to pathogens trains the innate immune system to work properly and this training period during early childhood is integral to the development and maturation of the innate immune system.
Dr. Alexander maintains that, when young children are given a COVID shot that uses messenger RNA (mRNA) technology, their innate immune systems do not have the opportunity to learn how to properly respond. He contends that the vaccine antibodies bind to the SARS-CoV-2 virus’s spike protein and prevent the innate immune system from doing its job. When the innate immune system is not able to develop naturally and learn how to differentiate between a normal cell and a pathogen, it can lead to
autoimmune disorders.3Dr. Alexander warned:
So, it is absolutely critical that the innate immune system, and particularly the innate antibodies very early on in childhood, be allowed this training.4
A well-functioning innate immune system is critical to the body’s effective response to a SARS-CoV-2 infection. A 2021 study in the Journal of Clinical Investigation Insight showed that children infected with COVID-19 fared better than infected adults because their innate immune prevented the virus from spreading.5 The study looked at 27 adults and 12 children infected with SARS-CoV-2 and found that the children’s innate immune system mounted a better response to the virus than the adults. The children displayed, “a more vigorous early mucosal immune response” than the adults, allowing them to recover from the virus faster.6
Changes to the Immune System Could Cause the Proliferation of Cancer Cells
A June 2022 study published in Food and Chemical Toxicology reported that COVID vaccination causes a significant change in type 1 interferon (INF type 1) signaling, initiates changes in short- and long-term immune competence and normal cellular function, and plays, “a critical role in both controlling viral proliferation and inducing antibody production.”7 The study points out that INF 1 cells stop the growth of virus and cancer cells and are critical for the immune system to successfully fight viruses such as SARS-CoV-2.
Because the COVID vaccination has been shown to interfere with the proper functioning of INF 1, the study authors, which include Stephanie Seneff, PhD, are concerned that patients who received the vaccine may be more susceptable to catching the virus in the first two weeks immediately after vaccination.8 They said the COVID shot could also interfere with the immune system’s recognition of and response to cancer cells because INF subtypes are especially important in preventing and recognizing cancer cells once they have formed.9
SAR-CoV-2 Spike Protein in COVID Shots and BRCA2 Associated Cancers
The study authors argue that the SARS-CoV-2 spike protein found in the COVID vaccines affects host cell exome production and causes the cells to create microRNA exomes that suppress the production of IRF9 and increase pro-inflammatory gene transcripts.10 They write:
IRF9 suppression via exosomal microRNA should also be expected to impair the cancer-protective effects of BRCA2 gene activity, which depends on that molecule for its activity … BRCA2-associated cancers include breast, fallopian tube, and ovarian cancer for women, prostate and breast cancer for men, acute myeloid leukaemia in children, and others.11
Given the universally recognized importance of optimally functioning BRCA1/2 for cancer prevention and given the central role of the TRAIL signal transduction pathway for additional cancer surveillance, the suppression of IRF7 and IRF9 through vaccination and subsequent SARS-CoV-2 spike glycoprotein production is extremely concerning for long-term cancer control in SARS-CoV-2 mRNA genetic vaccine injected populations.12
European Medicines Agency Issues Warning About Repeat Booster Doses
A study published in The Lancet provided evidence that immune function can be adversely affected by COVID vaccines. According to the study, those who received two doses of the vaccine had lower immune function after eight months than those who did not take the vaccine.13
One proposed cause of the decreased immune function is that N1 methylpseudouridine, which is part of the vaccine’s genetic code, could activate regulatory T cells and lead to lowered cellular immunity, which can prevent spike proteins from immediately decaying and, instead, circulating through the body for at least four months after vaccination. The authors note that lipid nanoparticles containing mRNA are inflammatory and have also been shown to accumulate in the ovaries, adrenal glands, liver and spleen, with the spike protein potentially causing vascular endothelial cells to be damaged and affect immune system organs.14
Adverse effects of COVID vaccines was confirmed by the European Medicines Agency (EMA), which recommended that frequent COVID vaccine boosters could negatively impact immune responses to the virus. The agency said that the booster doses should be spaced out further than every four months.
The head of EMA’s office of biological health threats and vaccines strategy, Marco Cavaleri, PhD, warned,
We are rather concerned about a strategy that entangles repeated vaccinations within a short term. We cannot really continuously give booster doses every 3-4 months… There are two concerns here: If we have a strategy in which we give boosters, let’s say, every four months approximately, we will end up potentially having problems with the immune response, and the immune response may not be as good as we would like it to be. So we should be careful in not overloading the immune system with repeated immunization. “And secondly, there is the risk of fatigue in the population with the continuous administration of boosters.”15
Reinhard Obst, PhD, professor at Ludwig Maximilian University’s Institute of Immunology in Germany, believes that Dr. Cavaleri’s warning is reasonable. He said:
The idea of vaccinating every four months or even more than that is novel. It’s something that you haven’t seen with other types of viruses. And the idea of T cell exhaustion is the reason why you might pause.16
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