 Dr
Nicholas Gonzalez has a clinic in New York and treats cancer patients
with a cancer diet therapy that includes pancreatic enzymes and a host
of natural compounds and vitamins as part of a total cancer nutrition
package. He completed a clinical trial on his therapy with patients
diagnosed with pancreatic cancer, supervised by the National Cancer
Institute and funded by Nestle. The results of that study were
published in the peer reviewed journal Nutrition and Cancer and reported
the ´best results ever in the treatment of the disease´.
Pancreatic enzymes, the Trophoblast, a diet therapy (an enzyme therapy) and cancer cure
(Chris Woollams, CANCERactive) Dr Nicholas J Gonzalez, MD has been
investigating nutritional approaches to cancer and other diseases since
1981 and has been in practice in New York since 1987. He has worked
with Linda L. lsaacs MD since 1985. As part of this, Gonzalez has
treated a variety of different cancers with great success.
Uniquely, Gonzalez has attempted to have full clinical trials behind his therapy. "We
did complete a trial of our therapy with patients diagnosed with
pancreatic cancer, supervised by the National Cancer Institute and
funded by Nestle. The results of that study were published in the peer
reviewed journal Nutrition and Cancer and reported the best results ever in the treatment of the disease.
As a result of that data, our US
National Cancer Institute funded a large-scale clinical trial,which
turned out to be, unfortunately, a nightmare of mismanagement. A paper
was published a year ago without our knowledge claiming our therapy
didn´t work, but the paper was a complete misrepresentation of the large
scale clinical trial.
I have written a lengthy rebuttal of the recently published article on our website at: http://www.dr-gonzalez.com/jco_rebuttal.htm." So says Dr Gonzalez in a note to me.
In 2012 Gonzalez went further - he published a book: What Went Wrong -
the truth behind the clinical trial of the enzyme treatment of
cancer´.
Dr Paul J Rosche, Clinical Professor of Medicine and Psychiatry, New York Medical School writes about the book of the trial as follows:
´This
book is about a $1.4 million grant awarded by the National Cancer
Institute in 1998 to do a controlled clinical trial comparing the
chemotherapeutic drug Gemzar to Dr Gonzalez enzyme approach in the
treatment of patients with pancreatic cancer. Dr Gonzalez documents how
the study was mismanaged, how he had no control over the selection of
patients, and how the protocol was violated in numerous ways that were
subsequently confirmed by regulatory authorities. Nevertheless, a
misleading article was published without his knowledge and none of the
responsible parties were (sic) ever admonished or held accountable. This
tragic tale tends to support a growing suspicion that the cancer cartel
of organizations, government agencies and vested interests is devoted
more to preserving their enormous profits and reputations than to the
prevention and cure of cancer´.
Why the fuss? Why would anyone want to misrepresent a Clinical Trial?
 The Trophoblast, and one solution to the medical enigma of our time
Gonzalez has developed an approach to pancreatic cancer, and indeed
any cancer, using a tailored Diet therapy and incorporating pancreatic
enzymes, which have ´cancer-killing´ properties. The theory behind this
work originated at Edinburgh University in the early twentieth century,
and Gonzalez interest was heightened during his period of study with
William Kelley DDS, who developed a general and successful cancer
treatment and recorded it in a book called "One Answer to Cancer".
In the earlier cases submitted in 1993 to the NCI, Gonzalez had
treated a variety of cancers in a variety of patients. Based on this
presentation, the NCI suggested he pursue a pilot study with patients
diagnosed with advanced pancreatic cancer - the theory being that
because of the seriousness of this cancer, clear results would be quick
to obtain. Cancer of the pancreas is rarely curable and five-year
survival rates are only 4 per cent in the USA.
Gonzalez and Isaacs completed a pilot study, published in 1999, showing
that patients on the Gonzalez regime lived on average 17.5 months - or three times longer than those taking conventional chemotherapy. So this is political dynamite.
The follow-up clinical trial used a nutritional therapy of supplements
(from vitamins to animal glandular products), plus coffee enemas and
pancreatic enzymes in patients diagnosed with Grade II, III and IV
pancreatic cancers. And it competed with a control group of patients
taking standard chemotherapy.
Though initially a minimum of 72 patients were to be enrolled in the
study, far fewer eventually were admitted by the Principal Investigator
at Columbia University.
The published paper from that trial, written without Dr. Gonzalez´s
knowledge or consent, according to Gonzalez ´misrepresented´ the
findings and claimed that chemotherapy had worked better when, in fact,
the majority of patients on the nutritional arm were unable or unwilling
to follow their treatment."
Clearly there is merit in the Gonzalez Therapy so let us look at the whole issue in a little more detail.
Dr. John Beard (1858-1924)
In 1906 a Mancunian embryologist working in Edinburgh, Dr John Beard,
proposed that pancreatic enzymes could represent the bodys main defence
against cancer.
First, he noticed that in the womb the implantation of the embryo
with its trophoblast into the uterus wall involved an incredibly precise
fusion of hormones and chemicals all within the space of a couple of
days. He also noticed that the placenta stopped growing on the precise
day that the pancreas of the foetus became active and started to secrete
its own enzymes (around day 56).
Since there was no logic to a foetus needing pancreatic enzymes for
digestion - nutrition is provided via the placenta in a pre-digested
form - he concluded that these pancreatic enzymes must have another
function.
Pancreatic enzymes may be orally ingested and are acid stable
Beard also noted that placental cells (trophoblast cells) looked
somewhat like cancer cells; they were undifferentiated, capable of very
rapid growth, invasion into nearby tissue, capable of forming new blood
cells and so on. All rather like a cancer cell.
And he hypothesised that if pancreatic enzymes could stop this growth maybe they could do it with cancer cells too.
He then took trypsin (a pancreatic enzyme) and injected it into mouse
sarcomas achieving a tumour regression in every case. At the time Beard
believed the enzymes had to be injected to bypass the stomachs
hydrochloric acid, but in recent years it has been demonstrated that
orally digested pancreatic enzymes are, in fact, acid stable and work
just as well.
Beard then developed what is called the Trophoblast Theory of Cancer.
The theory ran that the earliest blob of cells in the foetus was simply
a rapidly dividing mass of undifferentiated cells. But each of us has
such germ cells, or stem cells, in
our bodies throughout our lives - they circulate in our bodies to act
as precursor, healing cells. They arrive at a place of inflammation, or a
wound, and turn into the type of cell required to repair that
partricular problem. Repair is a continuous process in all of us.
However, sometimes these trophoblasts are not switched over to normal
stomach lining cells or liver cells, and instead continue to produce
more and more undifferentiated cells.
Beard believed oestrogen maintained these cancer-like cells whilst pancreatic enzymes neutralised them
Baird went on to theorise that the female sex hormone, oestrogen,
kept these trophoblast cells in their undifferentiated, rapidly dividing
state, whilst pancreatic enzymes like trypsin or chymotrypsin either
switched them over to normal cells or could in some way attack them,
enabling the immune system to recognise them and neutralise them.
He went further to suggest that cancer was rather like having a baby
growing in the wrong place at the wrtong time. Certainly Professor Wang
and his team in America in 2004, covered elsewhere on this web site,
concluded that stomach cancer could be formed when oestrogen kept stem
cells in their rapidly dividing form, rather than allowing them to
convert to normal, new and healthy stomach lining cells. He cal;lecd his
theory a revolutionary ´breakthrough´. Others may think he was 93 years
late!
In 1911 Dr Beard published The Enzyme Therapy of Cancer, but
after his death in 1924 the theory was basically forgotten, especially
with the advent of Marie Curie and her radiation work.
Dr W D Kelley
Gonzalez himself became interested in this theory when he was at
Cornell University Medical School in 1981. Gonzalez had met a Dr William
Donald Kelley, a dentist, who had actually been treating cancer
patients for 20 years. As part of his fourth years work he reviewed the
work of Kelley, a man much attacked by the establishment for his
theories, and this turned into a formal 2-year research project. In this
Gonzalez reviewed 50 of Kelleys patients initially given a poor
prognosis but all of whom enjoyed long term survival and cancer
regression with Kelleys regime.
Gonzalez then thoroughly analysed 22 patients, all of whom had
visited Kelley between 1974 and 1982 with pancreatic cancer. He
interviewed those still alive, relatives of the decreased and obtained
full medical records.
The study showed that Kelleys nutritional and enzyme approach had delivered results far beyond those of orthodox medicine
Despite a thorough 5-year research study, the report was met with
scorn and ridicule because, of course, it showed that Kelleys
nutritional and enzyme approach had delivered results far beyond those
of orthodox medicine.
The Kelley Approach
Kelley believed each of us has their own personal metabolic code. His
aim was to find this unique metabolism and stimulate it. Kelley took
the work of Beard and theorised that the formation of cancer was clear. Excess female hormones were responsible for changing a stem cell into a trophoblast cell.
In simple English, this means that cancer is the growth of normal
tissue, but at the wrong time and in the wrong place. It progresses
because of a lack of cancer digesting enzymes in the body and Kelley
believed the pancreas, through its enzymes, was the primary cancer
fighter in the body. So his solution was to get pancreatic enzymes to
the cancer site and inhibit the growth, but control the rate of attack,
otherwise toxins would flood the body and cause problems elsewhere.
Kelleys treatment was divided into five parts:
1: Nutritional therapy - to break
down the cancer cells; megavitamins, minerals, high dose vitamin C,
bioflavenoids, coenzymes, raw almonds, amino acids and raw beef formula
with pancreatic enzymes.
2: Detoxification - to cleanse
the dead cells and toxins from the body; laxative purges, Epsom salt,
fasts, lemon juice, coffee enemas (for anything from three weeks to 12
months).
3: Diet- to rebalance the body,
the cellular metabolism and the immune system; at the outset he
advocated a strict vegetarian diet, but modified this as he identified
different individual types. Indeed he strongly advocated Metabolic
typing - that your ideal diet for health needed to reflect your personal
metabolic type. In all he ended up with 10 different diet types and 95 variations.
4: Neurological stimulation - to
allow free flow of body energy, especially to cancer site; for example,
using osteopaths, chiropractors or physiotherapists. (A modern
equivalent might be the use of a cranial osteopath to manipulate not
just the skeletal structure but also the free-flow of body energy.)
5: Spiritual - to lift the spirits, and call upon the universal good; Kelley urged patients to trust in God, to read The Bible and to pray.
Kelley monitored a patients progress using his own Kelley Malignancy
System. Over a 20-year period, he reputedly treated 455 patients with 26
different cancers and claimed excellent results.
In 1986, probably due to endless criticism and pressure, Kelley
retired. However, Gonzalez took up the mantle in 1987. By July 1993 the
then Associate Director for Cancer Therapy at the NCI invited him to
present his work. What they saw proved interesting on a number of
different cancers.
What they saw proved interesting on a number of different cancers
Pancreatic cancer was chosen for formal trials because the prognosis
is so poor and so results could be obtained more noticeably and quickly.
To put it in context, at the same time as the Gonzalez preliminary
trial, 126 patients were treated with the FDA approved drug gemcitabine.
None lived past 19 months. On the original Gonzalez regime, despite
eight of his 11 patients starting out with Grade IV disease, five of the
11 survived 24 months, two actually surviving more than 48 months!
The Gonzalez Therapy
In fact, Gonzalez treats virtually all cancers and patients with MS
to chronic fatigue. Each treatment protocol is individually developed.
The therapy is complex and divided into three parts:
1: Diet
2: Ingressive supplementation (nutrient and enzymes)
3: Detoxification - The diet therapy varies by individual and cancer, and can be vegan or can require meat two to three times per day!
The supplements may number 120 - 175 per day, and are again tailored
to the individual, including vitamins, minerals and trace elements. The
aim is to improve overall metabolic function with nutrients. Every
patient also takes large quantities of freeze-dried porcine pancreatic
enzymes, which Gonzalez believes provide the anti-cancer activity.
Detoxification is essential as patients do go through a healing
crisis and develop flu-like symptoms. Coffee enemas are used twice per
day. Coffee enemas cause symptom relief for almost all patients.
Gonzalez doesnt just want to cure people. He wants his work properly
tested and FDA approved. If the tests prove positive, he then wants his
work included in orthodox mainstream medicine. With Linda Isaacs he has
written a book entitled ´The Trophoblast and the origins of cancer. One solution to the medical enigma of our time´. (2009 New Spring Press).
Gonzalez wanted his work properly tested and FDA approved
I have known a number of people who have visited his clinic in New York and all have been very impressed.
His work also shows up the ignorance of the quacks who continue to
state that ´diet can´t cure a cancer´, or that ´there are no clinical
trials to support diet as a cancer cure´.
New work has shown a variety of cancers (from some breast to some
brain cancers) are linked to oestrogen and stem cells. For example, in
2004 Professor Wang and his team at British Columbia University claimed
their findings (that oestrogen kept repair stem cells in the rapidly
dividing state preventing them from becoming new stomach lining cells)
was a ´Breakthrough´ in the understanding of stomach cancer. A
´Breakthrough´ it may well be - but the idea originated 98 years before
Wang´s results!
In 2012 three studies on the existence of cancer stem cells were published simulataneously in the journals Nature and Science.
Prior to these studies the idea that cancer stem cells existed was
controversial. Now they have been proven to exist and a further study
has shown their importance. Cancer tumours have a hierachy of cells, the
most important (and the ones that can regrow the tumour after it has
been knocked back by chemotherapy) are cancer stem cells.
Herman Acevedo
An interesting postscript to Beard´s theories was provided in 1995
when Professor Hernan Acevedo and his associates showed that the
synthesis and statement of LCG is a common biochemical denomination of
cancer. Acevedo found LCG present in 85 different cancers examined.
So what is LCG? When a stem cell is stimulated by oestrogen it should
produce a trophoblast according to Beard. A trophoblast in turn
releases a hormone called chorionic gonado trophin (LCG). Pregnancy
tests usually pick up on LCG in the blood, but a similar and much more
sensitive test could detect LCG produced by cancer cells. If such a test
could be developed - a sort of super pregnancy test kit - we would have
a cheap and less invasive way to detect cancer via the urine.
(Apparently there is indeed now a test for a similar hormone HCG,
human chorionic gonadotrophin (not LCG). An American Laboratory called
American Metabolic Laboratories in Hollywood, Florida does this test
and measures HCG in both blood and urine. A result greater than zero
indicates active cancer. The blood test does present false positives
though and the urine test is taken as a fail safe. A negative in the
urine suggests any positive result in the blood test is a false
positive. The test requires blood serum and urine shipped express.)
Interestingly when I was speaking on my UK tour, a lady told the room
that she had felt so ill she thought she might be pregnant and did a
test which was positive. It was only when she went to the doctor she
found she had cancer instead.
Either way it looks as though Beards theory over 100 years ago has
great merit. So why then is not more work underway? Could it be that
pancreatic enzymes are cheap, or no drugs are required? Or could it be
that no one receives a Nobel Prize for work that is 100 years old?
Worse, when we contacted UK vitamin manufacturers to see if we could buy
pancreatic enzymes we were told by a leading company that their sale
was banned in the UK.
_______________________________
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