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Are Vitamin C Pills Worth Taking? Don’t Ask Your Doctor!
July 14, 2014
None of this negative science discouraged laboratory researchers in
China however. They inoculated mice with influenza virus and then
injected 3 milligrams of vitamin C per gram of body weight. (Laboratory
rats weigh about 300-500 grams.) [University of Wisconsin] So these animals were injected with 900-1500 mg vitamin C.
A 70-kilogram (154-lb) human weighs in at 70,000 grams. So the amount of vitamin C the lab rats received was equivalent to 21,000 mg in a human weighing 154-lb (70 kilogram). That is a lot of vitamin C. Far lower doses of vitamin C can be used in humans to achieve maximal blood concentrations.
So what happened to the intentionally sickened mice? Well, the viral levels in their blood were 10-100 fold lower than untreated mice. The vitamin C-treated mice exhibited very little lung inflammation, which in turn lowered their death rate. [Chinese journal of tuberculosis and respiratory diseases May 2014]
So how does this animal lab research translate to humans? Carol Johnston, a long-time vitamin C researcher at Arizona State University took a small group of seemingly healthy non-smoking men (tobacco reduces vitamin C blood levels) whose vitamin C blood levels ranged from adequate to low and gave them 1000 mg of vitamin C/day for 8 weeks. Over that time 11 of the men who took an inactive placebo tablet and 7 men who took vitamin C develop cold symptoms, a 45% difference. Duration of cold symptoms declined -3.2 days in the vitamin C-treated group. Another bonus: the males in the vitamin C-treated group were more physically active (+39.6%).
A 70-kilogram (154-lb) human weighs in at 70,000 grams. So the amount of vitamin C the lab rats received was equivalent to 21,000 mg in a human weighing 154-lb (70 kilogram). That is a lot of vitamin C. Far lower doses of vitamin C can be used in humans to achieve maximal blood concentrations.
So what happened to the intentionally sickened mice? Well, the viral levels in their blood were 10-100 fold lower than untreated mice. The vitamin C-treated mice exhibited very little lung inflammation, which in turn lowered their death rate. [Chinese journal of tuberculosis and respiratory diseases May 2014]
So how does this animal lab research translate to humans? Carol Johnston, a long-time vitamin C researcher at Arizona State University took a small group of seemingly healthy non-smoking men (tobacco reduces vitamin C blood levels) whose vitamin C blood levels ranged from adequate to low and gave them 1000 mg of vitamin C/day for 8 weeks. Over that time 11 of the men who took an inactive placebo tablet and 7 men who took vitamin C develop cold symptoms, a 45% difference. Duration of cold symptoms declined -3.2 days in the vitamin C-treated group. Another bonus: the males in the vitamin C-treated group were more physically active (+39.6%).
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